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Diet Modification Slows PSA Doubling After Prostate Cancer Treatment

This Article was Written February 5th, 2009

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Diet Modification Slows PSA Doubling

After Prostate Cancer Treatment  

NEW YORK JAN 29, 2009 (Reuters Health) - A diet low in saturated fat, high in vegetable protein and low in animal protein is associated with a “substantial” increase in prostate-specific antigen (PSA) doubling time and an increase in quality of life in men treated for prostate cancer, according to results of a pilot study.As reported in the December issue of Urology, the study subjects were 36 men with biopsy-confirmed prostate cancer who had received primary treatment more than 6 months previously and who had increasing PSA levels.

Dr. James Carmody and colleagues at the University of Massachusetts Medical School in Worcester randomized subjects and their partners to attend 11 dietary and cooking classes emphasizing plant-based foods and fish, or to a control group. Dietary compliance, quality of life and PSA levels at baseline, after the 11-week intervention and again 3 months after intervention were assessed.

The intervention group consumed significantly less saturated fat, more vegetable protein and less animal protein, including dairy products, than controls. They also reported indicators of increased quality of life compared with controls.

“Although no significant change was found in the rate of PSA increase between the two groups, the mean PSA doubling time for the intervention group was substantially longer at the 3-month follow-up visit than that of the controls,” Dr. Carmody and colleagues report.

“Future trials should examine the effect of the prostate-healthy diet with a larger sample of men followed for a longer period,” they conclude.

SOURCE:

  • Urology 2008;72:1324-1328.
    “Reuters content is the intellectual property of Reuters Limited. Any copying, republication or redistribution of Reuters content, including by caching, framing or similar means, is expressly prohibited without the prior written consent of Reuters. Reuters shall not be liable for any errors or delays in content, or for any actions taken in reliance thereon.”

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